Since it was discovered that the risks of hormone therapy outweighed the benefits, researchers have been looking for a safe, normal way to ease the symptoms of Menopause
Individuals are currently staying recruited for any follow-up scientific trial of an treatment often known as MF101 manufactured by Bionovo, Inc. In its primary clinical trial, MF101 offered women inside the study with preliminary evidence of relief from such symptoms seeing that hot whizzes and night sweats, with no risks linked to hormone remedy.
The treatment being tested clinically targets just one of the two known female receptors-the estrogen receptor beta. Laboratory info has shown that MF101 will not cause the proliferation of breast or perhaps uterine cancer tumor cells the way in which hormone remedy can, producing the medication a more secure alternative to available today hormone therapies.
In 2002, the Might Health Gumption (WHI) Estrogen Plus Progestin Trial, with over sixteen, 000 women participants, was stopped early when it was found that the standard dosage of mixture hormone therapy increased the chance of breast cancer, heart stroke, heart attacks, blood clots and dementia.
“Given the void that exists for the safe and effective treatment for menopausal symptoms, the aim is always to discover and develop narrative drugs such as MF101 which could abate most of the symptoms that contain historically recently been treated with hormones, ” said Dr . Mary Tagliaferri. Tagliaferri can be co-author of “The New Menopause Reserve: The Experts Help you create Informed Decisions on HORMONE REPLACEMENT THERAPY, Natural Body hormone Therapy, Organic Therapies, Classic Chinese Medicine And More” (Avery, 2006) and Chief Medical Officer of Bionovo, which can be developing the drug.
The clinical trials will take place under the directorship of recognized researcher Doctor Deborah Grady at four leading academics medical centers.
Bionovo can expect this Stage 2 trial to be finished by the second quarter of 2018.
“If this new drug testifies to be effective, we will be providing health care practitioners having a treatment they will comfortably suggest to girls experiencing perimenopause, ” explained Dr . Tagliaferri.